CautionHypericaceae

St. John's Wort

Hypericum perforatum

Cut at midsummer, at the height of its power, it bleeds red.

Overview

St. John's Wort is one of the most extensively researched medicinal plants in the world, and one of the most complicated to recommend. Its effectiveness for mild to moderate depression is supported by more clinical evidence than almost any other herbal remedy; its interactions with pharmaceutical drugs are serious enough that those interactions now appear on medication leaflets. It is a plant that works, which is precisely why it requires care. It blooms at midsummer, around the feast of St. John — the 24th of June — and when you crush the bright yellow flowers between your fingers they bleed a vivid red-purple from the hypericin within. This is the plant's pigment, its protection, and its medicine. The old name for this colour was blood of the sun.

Botanical Notes

An upright perennial reaching 30–90cm with paired, oval leaves covered in pale translucent oil glands visible as tiny dots when held to the light, and scattered black glands at the leaf margins containing hypericin. Flowers are five-petalled, bright yellow, with numerous prominent stamens, produced in dense, branching clusters from June to September. Common throughout Europe, western Asia, and North America on disturbed, well-drained, often calcareous ground: roadsides, grassland, woodland edges, and waste places.

Lore & History

Gathered on Midsummer's Eve and hung in doorways and windows, St. John's Wort was the primary protective herb of the European summer solstice — burning it in bonfires drove away evil spirits; wearing it warded off witchcraft. The red of crushed hypericin was read as a symbol of the Baptist's blood, lending the plant a Christian legitimacy that older protective herbs lacked. Druids used it as a divination herb. In folk medicine from Britain to Russia, it was applied to wounds and burns as an oil — an application with genuine modern support for nerve tissue repair. The Welsh called it Llysiau Ifan — the herb of John — and gathered it in silence, at dawn, without looking back.

Warnings

St. John's Wort is a potent inducer of cytochrome P450 liver enzymes and P-glycoprotein — it significantly reduces the blood levels of a wide range of pharmaceutical drugs including antiretrovirals, cyclosporin, warfarin, certain antidepressants, and hormonal contraceptives. Do not take alongside prescription medications without medical consultation. May cause photosensitivity in pale-skinned individuals at high doses. Do not combine with SSRIs or other serotonergic drugs — risk of serotonin syndrome. Not to be used in severe depression.

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